Endocrine Abstracts

Background: Chemerin (CHEM) is a newly-discovered adipokine involved in the immune, metabolic and reproductive processes. Low-grade state inflammation (LGSI) is a key element in the pathogenesis of metabolic syndrome (MS).Objectives: The aim of the study was to assess the effect of age on MS prevalence, androgenic status as well as on selected inflammatory indices and CHEM plasma concentrations. Additionally we investigated correlations between CHEM and ...

Aims: The aim of our study was to assess the relationships between systemic markers of general inflammation: interleukin 18 (IL-18) and C-reactive protein (CRP) and dehydroepiandrosterone (DHEA) as well as dehydroepiandrosterone sulphate (DHEA-S) serum levels, in addition to the anthropometrical and biochemical indices of metabolic syndrome (MS) in men over the age of 40.Patients and methods: In 271 randomly chosen men aged 40 to 80 years living in Lubus...

Introduction: Vitamin D is postulated to play a significant role in the immune system modulation and its deficiency has been reported in some autoimmune disorders. Polymorphisms of different vitamin D-related genes, among them vitamin D receptor gene (VDR), could either be a risk factor for autoimmune diseases. Therefore the aim of the study was to assess the association between VDR Cdx2 (rs11568820) polymorphism and autoimmune thyroid disease (AITD) among th...